Hyperbaric oxygenation (HBO), as an adjuvant treatment in necrotizing soft tissues infections and in gas gangrene is reviewed, including its specific effects, experimental studies and clinical reports. With a global therapeutic management, considered as an emergency state, including surgery, antibiotic regimens and HBO, we can obtained 50% mortality and morbidity decrease with a more conservative surgery. Finally, favorable outcome is associated with early therapeutics and localization of the initial necrotizing infection.
Wattel, Mathieu, Neviere, Chagnon, , , , , (1992). [Role of hyperbaric oxygenation in the treatment of acute anaerobic infections]. Chirurgie; memoires de l’Academie de chirurgie, 1992 ;118(10):615-20. https://www.ncbi.nlm.nih.gov/pubmed/1345693