Successful treatment for sorafenib-induced liver dysfunction: a report of case with liver biopsy.
Abstract: Sorafenib is an oral multikinase inhibitor with anti-proliferative and anti-angiogenic effects and is used worldwide for the treatment of advanced or metastatic hepatocellular carcinoma (HCC). While the significant survival benefit of sorafenib in patients...
Severe small bowel pneumatosis in adult heart transplant recipient.
Abstract: Girardin, Garretto, Germani, Livi, Burra, , , , (2015). Severe small bowel pneumatosis in adult heart transplant recipient. Transplant international : official journal of the European Society for Organ Transplantation, 2015...
Molecular mechanisms of pharmacological doses of ascorbate on cancer cells.
Abstract: Intravenous application of high-dose ascorbate (vitamin C) has been used in complementary medicine since the 1970s to treat cancer patients. In recent years it became evident that high-dose ascorbate in the millimolar range bears selective cytotoxic effects...
Pentoxifylline-tocopherol-clodronate combination: A novel treatment for osteoradionecrosis of the temporal bone.
Abstract: Osteoradionecrosis (ORN) of the temporal bone is a complication of radiation therapy that is extremely challenging to manage. We report the case of a patient treated at our institution and present a review of the literature. A 52-year-old woman presented...
Cerebral arterial gas embolism in a professional diver with a persistent foramen ovale.
Abstract: A 33-year-old, male professional scallop diver diving on the Outer Hebrides in Scotland rapidly developed symptoms of cerebral arterial gas embolism following a provocative dive with possibly a fast ascent. During transfer by helicopter to the mainland for...
Fournier’s gangrene. A clinical review.
Abstract: Fournier's gangrene is a rare, necrotising fasciitis of the external genitalia, perineal or perianal regions. The disease has a higher incidence in males and risk factors for development include diabetes, HIV, alcoholism and other immune-compromised states....
Effect of hyperbaric oxygen on MMP9/2 expression and motor function in rats with spinal cord injury.
Abstract: To study the effect of hyperbaric oxygen intervention on the microenvironment of nerve regeneration after spinal cord injury modeling and to explore the possible mechanism of nerve regeneration and functional recovery in rats with spinal cord injury. In 98...
Beneficial effects of hyperbaric oxygen on edema in rat hippocampus following traumatic brain injury.
Abstract: Hyperbaric oxygen (HBO) therapy helps alleviate secondary injury following brain trauma [traumatic brain injury (TBI)], although the mechanisms remain unclear. In this study, we assessed recovery of post-TBI spatial learning and memory in rats using the...
Effect of mesenchymal stem cells transplantation combining with hyperbaric oxygen therapy on rehabilitation of rat spinal cord injury.
Abstract: To investigate the effect of BMSCs transplantation plus hyperbaric oxygen (HBO) on repair of rat SCI. Seventy five male rats were divided randomly into five groups: sham, vehicle, BMSCs transplantation group, combination group, 15 rats in each group. Every...