Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model
Abstract Background:Â Mitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer's disease (AD), with morphological and functional abnormalities limiting the electron transport chain and ATP production. A contributing factor of...
Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma.
Abstract: Hyperbaric oxygen therapy (HBOT) is used in the treatment of radiation-induced tissue injury but its effect on (residual) tumor tissue is indistinct and therefore investigated in this study. Orthotopic FaDu tumors were established in mice, and the response...
Treatment of nipple-sparing mastectomy necrosis using hyperbaric oxygen therapy.
Abstract: Alperovich, Harmaty, Chiu, , , , , , (2015). Treatment of nipple-sparing mastectomy necrosis using hyperbaric oxygen therapy. Plastic and reconstructive surgery, 2015 Jun;135(6):1071e-1072e. https://www.ncbi.nlm.nih.gov/pubmed/25724049
Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain.
Abstract: Nerve injury is associated with microvascular disturbance; however, the role of the vascular system has not been well characterized in the context of neuropathic pain. Furthermore, ischemia is thought to play a role in a number of neuropathic pain...
Effect of pulsed electromagnetic field treatment on programmed resolution of inflammation pathway markers in human cells in culture
Abstract Inflammation is a complex process involving distinct but overlapping biochemical and molecular events that are highly regulated. Pulsed electromagnetic field (PEMF) therapy is increasingly used to treat pain and edema associated with inflammation following...
Effects of hyperbaric oxygen on Pseudomonas aeruginosa susceptibility to imipenem and macrophages.
Abstract: The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen...
Sternoclavicular joint septic arthritis with chest wall abscess in a healthy adult: a case report.
Abstract: Septic arthritis of the sternoclavicular joint is rare. It can be associated with serious complications such as osteomyelitis, chest wall abscess, and mediastinitis. In this report, we describe a case of an otherwise healthy adult with septic arthritis of...
The continuance time of pressure effect in the rat model of complete Freund’s adjuvant induced arthritis.
Abstract: We previously published on the pressure effect using a rheumatoid animal model (Pain Physician in 2013 and 2014). However, we do not know how long the pressure effect lasts after exposure to high pressure. We evaluated the duration of the pressure effect in...
[Cerebellar abscess due to infection with the anaerobic bacteria fusobacterium nucleatum: a case report].
Abstract: We report a rare case of cerebellar abscess produced by anaerobic bacteria. A 76-year-old man was admitted to our hospital with a history of fever, vomiting, and dizziness lasting 14 days. Computed tomography(CT)scan and magnetic resonance images showed the...