Evodiamine inhibits proliferation and induces apoptosis in gastric cancer cells.
Abstract: In the present study, the effects of evodiamine on the apoptosis of human gastric cancer cells was studied in order to assess its antitumor effects and identify the molecular mechanisms involved. SGC7901 gastric cancer cells were treated with evodiamine at...
Hyperbaric Oxygen for Wounds and Diabetic Ulcers
Lawrence already had half of his foot removed when he first visited the Memorial Hospital Center For Wound Healing and Hyperbaric Oxygen Therapy at Memorial Hospital Pembroke. The therapy helped saved his leg from being amputated.
Hyperbaric oxygen treatment outcome for different indications from a single center.
Abstract: Hyperbaric oxygen (HBO) is used as an adjunctive therapy for a variety of indications. However, there is a lack of high-quality research evaluating HBO treatment outcomes for different indications available in the current literature. We retrospectively...
Preconditioning with hyperbaric oxygen in pancreaticoduodenectomy: a randomized double-blind pilot study.
Abstract: In a prospective randomized double-blind study, we evaluated the post-operative biological and clinical effects of a single preoperative hyperbaric-treatment the day before surgery for pancreatic ductal adenocarcinoma. Twenty one patients were randomized and...
Osteoradionecrosis of the temporal bone: a case series.
Abstract: To study osteoradionecrosis (ORN) of the temporal bone. Retrospective case review. Academic medical center. Patients were included who had previously undergone radiation to the head and neck and then developed exposed necrotic bone within the ear canal that...
Hyperbaric oxygen therapy for hemorrhagic cystitis.
Abstract: Gökçe, Akçay, Tuğcu, Erdemir, Mirasoğlu, , , , (2014). Hyperbaric oxygen therapy for hemorrhagic cystitis. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2014...
Cystectomy for refractory hemorrhagic cystitis: contemporary etiology, presentation and outcomes.
Abstract: We evaluate the clinical presentation, management and outcomes of patients undergoing cystectomy for refractory hemorrhagic cystitis. We identified 21 patients with refractory hematuria treated with cystectomy at our institution between 2000 and 2012. Clot...
Diabetic foot ulcer: an evidence-based treatment update.
Abstract: Diabetic foot ulcers (DFUs) are extremely debilitating and difficult to treat. Multidisciplinary management, patient education, glucose control, debridement, offloading, infection control, and adequate perfusion are the mainstays of standard care endorsed by...
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression
Abstract Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell populations, leading to signal transduction changes in long-term hematopoietic...