Management of open wounds: lessons from orthopedic oncology.
Abstract: The management of complex wounds remains a challenge, and although there have been many promising advances, patients often undergo a morbid and lengthy process to obtain sufficient, satisfactory healing. Sarcoma patients are especially vulnerable to soft...
Late consequential surgical bed soft tissue necrosis in advanced oropharyngeal squamous cell carcinomas treated with transoral robotic surgery and postoperative radiation therapy.
Abstract: A subset of patients with oropharyngeal squamous cell carcinoma (OP-SCC) managed with transoral robotic surgery (TORS) and postoperative radiation therapy (PORT) developed soft tissue necrosis (STN) in the surgical bed months after completion of PORT. We...
Administration of a second generation perfluorochemical in combination with hyperbaric oxygenation does not provide additional benefit in a model of permanent middle cerebral artery occlusion in rats.
Abstract: Both, second generation perfluorochemicals (Oxycyte®) and hyperbaric oxygen (HBO) have been shown to reduce necrotic tissue volume if administered early after experimental cerebral ischemia. With the idea of exponentiation of oxygen delivery to ischemic...
Hyperbaric oxygen therapy ameliorates local brain metabolism, brain edema and inflammatory response in a blast-induced traumatic brain injury model in rabbits.
Abstract: Many studies suggest that hyperbaric oxygen therapy (HBOT) can provide some clinically curative effects on blast-induced traumatic brain injury (bTBI). The specific mechanism by which this occurs still remains unknown, and no standardized time or course of...
The effect of hyperbaric oxygen therapy on treatment of wound complications after oral, pharyngeal and laryngeal salvage surgery.
Abstract: Radiation therapy alone, or combined with chemotherapy, are both used for cancer in the head and neck. This can lead to damage of tissue cells and vasculature. Surgery in such compromised tissues has increased complication rates, because wound healing with...
Iron deficiency anemia–bridging the knowledge and practice gap.
Abstract: Despite its high prevalence, anemia often does not receive proper clinical attention, and detection, evaluation, and management of iron deficiency anemia and iron-restricted erythropoiesis can possibly be an unmet medical need. A multidisciplinary panel of...
Department of Defense trials for hyperbaric oxygen and TBI: issues of study design and questionable conclusions.
Abstract: Harch, , , , , , , , (). Department of Defense trials for hyperbaric oxygen and TBI: issues of study design and questionable conclusions. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc,...
Reply: Department of Defense trials for hyperbaric oxygen and TBI: issues of study design and questionable conclusions.
Abstract: Weaver, Cifu, Hart, Wolf, Miller, , , , (). Reply: Department of Defense trials for hyperbaric oxygen and TBI: issues of study design and questionable conclusions. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc,...
Regulatory considerations for a traumatic brain injury (TBI) indication for hyperbaric oxygen (HBO2).
Abstract: Weaver, Dicks, Deru, Miller, , , , , (). Regulatory considerations for a traumatic brain injury (TBI) indication for hyperbaric oxygen (HBO2). Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc,...