Management and prevention of diabetic foot ulcers and infections: a health economic review.
Abstract: Diabetic foot ulcers and infections are common and incur substantial economic burden for society, patients and families. We performed a comprehensive review, on a number of databases, of health economic evaluations of a variety of different prevention,...
Hyperbaric oxygen does not improve outcome in patients with necrotizing soft tissue infection.
Abstract: Patients with necrotizing soft tissue infections (NSTIs) require prompt surgical debridement, appropriate intravenous antibiotics, and intensive support. Despite aggressive treatment, their mortality and morbidity rates remain high. The benefit of hyperbaric...
Management of brain abscesses in children treated for acute lymphoblastic leukemia.
Abstract: Brain abscesses in children with leukemia or other malignancies are rare and potentially fatal. We report on four children who developed brain abscesses during treatment for acute lymphoblastic leukemia (ALL). All patients received multimodal broad-spectrum...
Clinical correlate of brain SPECT perfusion abnormalities in fibromyalgia
Abstract The purpose of this study was to investigate the specific clinical correlate of brain SPECT perfusion abnormalities reported in fibromyalgia. Methods: We performed a whole-brain voxel-based correlation analysis involving regional cerebral blood flow and...
Is early diagnosis of necrotizing fasciitis important?
Abstract: Bennett, , , , , , , , (2008). Is early diagnosis of necrotizing fasciitis important? ANZ journal of surgery, 2008 Nov;78(11):947-8. https://www.ncbi.nlm.nih.gov/pubmed/18959691
Hypoxia enhances the replication of oncolytic herpes simplex virus.
Abstract: Hypoxia contributes to the resistance of tumors to conventional therapies. We hypothesized that their replication in hypoxic environments like brain or oral mucosa would make oncolytic herpes simplex viruses (HSVs) such as G207 (which has undergone clinical...
Surgical management of surgery and radiation induced peristomal neck ulcerations.
Abstract: PROBLEMS/OBJECTIVE: Non-healing cervical skin ulcerations with concomitant necrosis of the subcutaneous tissue and muscle is a rare but feared complication of radiotherapy that can arise in cervical regions. Constant erosion of the surrounding tissue by the...
Surgical management of surgery and radiation induced peristomal neck ulcerations.
Abstract: PROBLEMS/OBJECTIVE: Non-healing cervical skin ulcerations with concomitant necrosis of the subcutaneous tissue and muscle is a rare but feared complication of radiotherapy that can arise in cervical regions. Constant erosion of the surrounding tissue by the...
Increased distribution of carboplatin, an anti-cancer agent, to rat brains with the aid of hyperbaric oxygenation.
Abstract: 1. The distribution of an anti-cancer agent carboplatin to brains was investigated in combination with hyperbaric oxygenation treatment in rats. 2. After intravenous administration of carboplatin (30 mg kg(-1)) to male Wistar rats, elimination curves of...