Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis.
Approximately 1 in 5 adults in the United States are affected by the pain, disability, and decreased quality of life associated with arthritis. The primary focus of treatment is on reducing joint inflammation and pain through a variety of pharmacotherapies, each of which is associated with various side effects. Hyperbaric oxygen therapy is an alternative treatment that has been recommended to treat a variety of inflammatory diseases, ranging from chronic brain injury to exercise induced muscle soreness. The purpose of this set of experiments was to explore the effect of hyperbaric oxygen therapy on joint inflammation and mechanical hyperalgesia in an animal model of arthritis, and compare these effects to treatment with aspirin. Hyperbaric oxygen therapy significantly reduced both joint inflammation and hyperalgesia. As compared with aspirin treatment, hyperbaric treatment was equally as effective in decreasing joint inflammation and hyperalgesia. This article reports that hyperbaric oxygen treatment decreases pain and inflammation in an animal model of arthritis. The effect of hyperbaric oxygen treatment is very similar in magnitude to the effect of acetylsalicylic acid treatment. Potentially, hyperbaric oxygen could be used to treat pain and inflammation in patients with arthritis.
A different approach to the management of necrotizing fasciitis in neonates: hyperbaric oxygen.
Abstract: Aydinoz, Yildiz, , , , , , , (2007). A different approach to the management of necrotizing fasciitis in neonates: hyperbaric oxygen. International wound journal, 2007 Mar;4(1):94-5. https://www.ncbi.nlm.nih.gov/pubmed/17425553
Phagocytic activity of neutrophils improves over the course of therapy of diabetic foot infections.
Abstract: The aim of this study was to investigate changes in phagocytic activity of neutrophils of type 2 diabetic patients with foot infections over short treatment courses. The potential utility of the phagocytic index in determining the efficacy of treatment...
Phagocytic activity of neutrophils improves over the course of therapy of diabetic foot infections.
Abstract: The aim of this study was to investigate changes in phagocytic activity of neutrophils of type 2 diabetic patients with foot infections over short treatment courses. The potential utility of the phagocytic index in determining the efficacy of treatment...
Radiation cystitis: indication for hyperbaric oxygen.
Abstract: Witucki, , , , , , , , (2009). Radiation cystitis: indication for hyperbaric oxygen. The Journal of emergency medicine, 2009 Apr;36(3):296-7. https://www.ncbi.nlm.nih.gov/pubmed/18325711
Mitochondrial delivery is essential for synaptic potentiation
Abstract Mitochondria, as portable generators that power synaptic function, regulate the ATP supply and calcium homeostasis in the neuron. As molecular interactions within the synapses before and after the potentiation are beginning to be elucidated, the deciding...
Necrotizing fasciitis: case report and review of literature.
Abstract: We report a case of necrotizing fasciitis of the lower limb. This medico-surgical emergency is a life-threatening invasive soft-tissue infection which primarily involves the fascia superficialis and rapidly extends along subcutaneous tissue with relative...
Treatment of gastrointestinal radiation injury with hyperbaric oxygen.
Abstract: Chronic radiation enteritis develops in 5-20% of patients following abdominal and pelvic radiation. Current treatments are largely ineffective. To assess the effectiveness of hyperbaric oxygen therapy (HBO2) as a treatment for chronic radiation enteritis and...
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Abstract: Radiation-induced fibrosis (RIF) and radionecrosis (RN) are late complications that are usually considered irreversible. Usual management strategy includes eliminating local and general aggravating factors and controlling acute and chronic inflammation with...