Thoughts on B-vitamins and dementia
Abstract The B-vitamins, including vitamins B12, B6, B1, B2, niacin (B3) and folate (B9), have been implicated as protective risk factors against cognitive decline and Alzheimer's disease. This commentary reviews the evidence to support protective relations of these...
Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy.
Abstract: Hyperbaric oxygen therapy (HBOT) has been used to treat refractory wounds for the last several decades, with the majority of research focusing on wounds secondary to arterial insufficiency. We describe 2 patients with scleroderma with intractable bilateral...
Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis.
Abstract: To report a pediatric case of posttraumatic fungal fasciitis treated successfully with a combination including posaconazole. Case report. Pediatric critical care unit at Antwerp University Hospital. A 12-yr-old female polytrauma patient, suffering from...
Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma and breast cancer.
Abstract: Osteonecrosis of the jaw is an unremitting adverse outcome associated with bisphosphonate therapy in patients with multiple myeloma or bone metastases from solid tumors. Twelve patients who presented with exposed bone associated with bisphosphonates were...
Adjunctive hyperbaric oxygen therapy in radiation-induced non-healing wound.
Abstract: Korpinar, Cimsit, Cimsit, Bugra, Buyukbabani, , , , (2006). Adjunctive hyperbaric oxygen therapy in radiation-induced non-healing wound. The Journal of dermatology, 2006 Jul;33(7):496-7. https://www.ncbi.nlm.nih.gov/pubmed/16848825
Impact of perioperative hyperbaric oxygen therapy on the quality of life of maxillofacial patients who undergo surgery in irradiated fields.
Abstract: From 2001 to 2005, 66 patients referred for perioperative hyperbaric oxygen therapy (HBO2) for debridement of necrotic tissue or prevention of radionecrosis were assessed with quality of life measures, before and after completion of HBO2 and surgery. The...
Apoptosis of T-leukemia and B-myeloma cancer cells induced by hyperbaric oxygen increased phosphorylation of p38 MAPK.
Tumor cells with different origins have different threshold to apoptosis. Hematopoietic (Jurkat, NCI-H929) cells and non-hematopoietic (A549, MCF-7) cells were received hyperbaric oxygen (HBO(2)) treatment from 2.5 to 3.5 atmosphere absolute (ATA) of 100% oxygen for 6h, and a significant percentage of apoptosis were shown only in hematopoietic Jurkat and NCI-H929 cells by either Annexin V or TUNEL assay. Oxidative stress was illustrated higher in HBO(2)-treated hematopoietic cells by superoxide fluorochrome detectors. HBO(2) treatment leads to caspase-3, caspase-7 activation and further cleavage of PARP within cells. Furthermore, the increased phosphorylation of p38 MAPK was demonstrated in both Jurkat and NCI-H929 cells.
Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury.
Abstract: Recently, the effect of hyperbaric oxygen (HBO(2)) therapy was explored in the treatment of chronic TBI. It has been speculated that idling neurons in the penumbra zone remain viable several years after injury and might be reactivated by enhanced...
Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury.
Abstract: Recently, the effect of hyperbaric oxygen (HBO(2)) therapy was explored in the treatment of chronic TBI. It has been speculated that idling neurons in the penumbra zone remain viable several years after injury and might be reactivated by enhanced...