Hyperbaric oxygen therapy: caveat doctor!
Abstract: In the right hands, hyperbaric oxygen therapy is a safe and legitimately employed treatment modality for some specific medical conditions. It is not a panacea. It is a prescriptive treatment which should be administered only under the direct supervision of a...
[Toxic Epidermal Necrolysis (Lyell syndrome): a pathology for burn units].
Abstract: Toxic Epidermal Necrolysis (Lyell's syndrome) is a rare but very serious dermatological lesion, characterized by the sudden onset of high fever, signs of systemic toxicity and intense mucocutaneous exfoliation. Its pathophysiology is not yet well determined,...
Systemic ondansetron antagonizes the sensory block produced by intrathecal lidocaine.
Abstract: In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the...
Necrotizing fasciitis: pathogenesis and treatment.
Abstract: Necrotizing fasciitis is a rapidly progressive, life-threatening infection and a true infectious disease emergency. Despite much clinical experience, the management of this disease remains suboptimal, with mortality rates remaining approximately 30%....
Depression in multiple sclerosis: A review
Abstract Several studies have reported high rates of depression in multiple sclerosis (MS) with a lifetime prevalence of approximately 50% and an annual prevalence of 20% not uncommon. Concern about the potential of new drug treatments to exacerbate or precipitate...
Management of extensive osteoradionecrosis of the mandible with radical resection and immediate microvascular reconstruction.
Abstract: Osteoradionecrosis (ORN) is a severe and devastating late complication of radiotherapy in patients with head and neck cancer. Management of ORN remains controversial and the current approach has been focused on debridement, systemic antibiotics, and...
Management of extensive osteoradionecrosis of the mandible with radical resection and immediate microvascular reconstruction.
Abstract: Osteoradionecrosis (ORN) is a severe and devastating late complication of radiotherapy in patients with head and neck cancer. Management of ORN remains controversial and the current approach has been focused on debridement, systemic antibiotics, and...
Nonpharmacologic treatment of migraine.
Abstract: Nonpharmacologic treatment of migraine is often used by patients and can provide interesting options for physicians. Knowledge about the evidence and its absence is important. Avoidance of trigger factors can help, if individualized. Behavioral approaches,...
Acute and severe hypobaric hypoxia increases oxidative stress and impairs mitochondrial function in mouse skeletal muscle
Abstract Severe high-altitude hypoxia exposure is considered a triggering stimulus for redox disturbances at distinct levels of cellular organization. The effect of an in vivo acute and severe hypobaric hypoxic insult (48 h at a pressure equivalent to 8,500 m) on...