Osteoradionecrosis of the mandible: a review.

Abstract: Osteoradionecrosis (ORN) is a complex metabolic and tissue homeostatic deficiency created by radiation-induced tissue injury. Although infection was initially felt to play an important role in its pathogenesis, the role of microorganisms has been relegated...

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Criteria for bone debridement in massive lower limb trauma.

Abstract: Adequate debridement remains the most important factor in prevention of chronic sepsis in cases of massive lower limb trauma. Despite treatment with chronic antibiotics, muscle flaps, hyperbaric oxygen, and/or free-tissue transfer, failures are common due to...

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