Late results of a trial of hyperbaric oxygen and radiotherapy in head and neck cancer: a rationale for hypoxic cell sensitizers?
Abstract: 104 patients with head and neck cancer were entered into a prospective controlled trial of radiotherapy in hyperbaric oxygen (HBO). The trial compared 10 fractions of radiotherapy in HBO with 30 fractions of radiotherapy in air. Survival and local control...
Irradiation with misonidazole and hyperbaric oxygen: final report on a randomized trial in advanced head and neck cancer.
Abstract: One hundred and thirty patients with locally advanced squamous carcinoma of the head and neck were treated in a prospective randomized trial to compare conventional irradiation (63.00 Gy in 30 fractions) with a combination sensitizer regimen of misonidazole...
Effect of hypothermia on radiosensitization.
Abstract: Hypothermia reduces metabolism and oxygen utilization by tissues. If the blood supply to a solid tumour can be maintained at a sufficient level, the hypoxic fraction of tumour cells may be reduced and radiosensitivity increased. This may be achieved if...
Partial hypoxia as a cause of radioresistance in a human tumor xenograft: its influence illustrated by the sensitizing effect of misonidazole and hyperbaric oxygen.
Abstract: While previous studies with three human tumor xenografts suggest that contact-resistance plays a major role in the response of these tumors to radiation, it remains possible that partial hypoxia may provide an alternate explanation. The present study was...
Oxygen delivery to tumors.
Abstract: Sensitization of hypoxic cells in tumors, by increasing their oxygen supply, has been attempted for at least 30 years. Only the use of hyperbaric oxygen has been shown unequivocally as a beneficial adjunct to radiotherapy; and even then, the number of sites...
Hyperbaric oxygenation and erythrocyte antioxidant enzymes in multiple sclerosis patients.
Abstract: Erythrocyte glutathione peroxidase, catalase, and superoxide dismutase activities were measured in 18 patients with clinically definite MS, and results compared with those from neurological controls. These studies indicated that glutathione peroxidase...
[Retinitis pigmentosa and hyperbaric oxygen therapy].
Abstract: Vérin, Comte, Poisot, , , , , , (). [Retinitis pigmentosa and hyperbaric oxygen therapy]. Bulletin des societes d'ophtalmologie de France, ;86(8-9):1071-2, 1074. https://www.ncbi.nlm.nih.gov/pubmed/3568248
Hyperbaric oxygen therapy in chronic stable multiple sclerosis: double-blind study.
Abstract: We carried out a randomized, double-blind, placebo-controlled trial of hyperbaric oxygen therapy (HBO) in patients with chronic stable MS. Eighty-two patients were treated in a multiplace hyperbaric chamber with gas supplied by mask. Forty-one patients...
[Changes in central hemodynamics in patients with ischemic stroke and possibilities of hyperbaric oxygenation in their correction].
Abstract: Isakov, Pravdenkova, Shelkovskiĭ, , , , , , (). [Changes in central hemodynamics in patients with ischemic stroke and possibilities of hyperbaric oxygenation in their correction]. Anesteziologiia i reanimatologiia,...