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Selective spleen tyrosine kinase inhibition delays autoimmune arthritis in mice.

by Extivita | Jul 8, 2014 | Rheumatoid Arthritis

Abstract: Spleen tyrosine kinase (SYK) has an important role in immunoreceptor signaling, and SYK inhibition has accordingly attenuated immune-mediated injury in several models. Therefore, the present study examined the effect of SYK inhibition with the selective...

Therapeutic effect of prolonged hyperbaric oxygen in adjuvant arthritis of the rat.

by Extivita | Apr 1, 1979 | Rheumatoid Arthritis

Abstract: Development of adjuvant disease in the rat is suppressed if hyperbaric oxygen is administered within one day after the inoculation of an oil suspension of Mycobacterium tuberculosis and continued for 16 to 17 days. Although 10 to 40% of the rodents developed...

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    Hyperbaric Oxygen Therapy (HBOT) Clinic located in Research Triangle Park, North Carolina (RTP, Raleigh, Durham, Chapel Hill).