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Pentoxifylline-tocopherol-clodronate combination: A novel treatment for osteoradionecrosis of the temporal bone.

by Extivita | Mar 22, 2015 | Cancer

Abstract: Osteoradionecrosis (ORN) of the temporal bone is a complication of radiation therapy that is extremely challenging to manage. We report the case of a patient treated at our institution and present a review of the literature. A 52-year-old woman presented...

Management of bisphosphonate-related osteonecrosis of the jaw: a literature review.

by Extivita | Jan 6, 2015 | Myeloma

Abstract: Osteonecrosis of the jaw (ONJ) is a serious side effect of bisphosphonate use in patients with osteoporosis, Paget’s disease, hypercalcemia of malignancy, metastatic bone disease and multiple myeloma, although recently this complication has also been...

What is the role of hyperbaric oxygen in the management of bisphosphonate-related osteonecrosis of the jaw: a randomized controlled trial of hyperbaric oxygen as an adjunct to surgery and antibiotics.

by Extivita | Dec 22, 2011 | Myeloma

Abstract: This study tested hyperbaric oxygen (HBO) as an adjunct to surgery and antibiotics in the treatment of bisphosphonate-related osteonecrosis of the jaw (ONJ) and evaluated its effects on gingival healing, pain, and quality of life. The investigators...

Osteonecrosis of the jaw after a single bisphosphonate infusion in a patient with metastatic renal cancer treated with sunitinib.

by Extivita | Jun 5, 2010 | Carcinoma

Abstract: Osteonecrosis of the jaw (ONJ) is recognised as an important adverse effect of intravenous bisphosphonates. Recent reports have suggested that antiangiogenic agents may promote the development of this condition. We report a case of ONJ occurring within days...

Bisphosphonate-related osteonecrosis of the jaw around dental implants in the maxilla: report of a case.

by Extivita | Oct 2, 2009 | Cancer

Abstract: We describe a patient who developed bisphosphonate (BP)-related osteonecrosis of the jaw (ONJ) around implants in the upper molar area. The patient was a 54-year-old woman with ulceration of the gum, bone exposure, and severe spontaneous pain around implants...
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    Hyperbaric Oxygen Therapy (HBOT) Clinic located in Research Triangle Park, North Carolina (RTP, Raleigh, Durham, Chapel Hill).