by Extivita | Jun 30, 2016 | Chronic Wounds
Abstract: Radiotherapy is effective in the treatment of tumors in the pelvic area but is associated with side effects such as cystitis and proctitis. Hyperbaric Oxygen Therapy (HBOT) has emerged as a treatment modality for radiation-induced side effects. In a rat...
by Extivita | Jan 27, 2016 | Rheumatoid Arthritis, Traumatic Brain Injury (TBI)
Abstract: The aim of this study was to investigate the efficacy of hyperbaric oxygen in secondary brain injury after trauma and its mechanism in a rat model. A rat model of TBI was constructed using the modified Feeney’s free-fall method, and 60 SD rats were...
by Extivita | Apr 29, 2015 | Chronic Wounds
Abstract: Several studies have shown a pathological oxygenation (hypoxia/hyperoxia) on the adipose tissue in obese subjects. Additionally, the excess of body weight is often accompanied by a state of chronic low-degree inflammation. The inflammation phenomenon is a...
by Extivita | Jan 7, 2015 | Stroke
Abstract: To examine the effects of hyperbaric oxygen (HBO) therapy and knockout of toll-like receptor 4 (TLR4) on the outcome of temporary middle cerebral artery occlusion (MCAO) in a mouse model. MCAO was induced in anesthetized male C57Bl/6 mice (WT) and TLR4...
by Extivita | Nov 30, 2014 | Spinal Cord Injuries
Abstract: The immunoreactive responses are a two-edged sword after spinal cord injury (SCI). Macrophages are the predominant inflammatory cells responsible for this response. However, the mechanism underlying the effects of HBOT on the immunomodulation following SCI...
