Intrathecal midazolam combined with low-dose bupivacaine improves postoperative recovery in diabetic mellitus patients undergoing foot debridement.
Abstract: Intrathecal midazolam acts synergically with other anesthetics to relieve surgical pain, and the drug combination may decrease complications attributable to each component drug. This prospective study was to determine the spinal effects of low-dose of...
Hyperbaric oxygenation for tumour sensitisation to radiotherapy.
Abstract: Cancer is common and radiotherapy is one well-established treatment for some solid tumours. HBO may improve the ability of radiotherapy to kill hypoxic cancer cells, so the administration of radiotherapy while breathing HBO may result in a reduction in...
Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury
Abstract Reactive oxygen species (ROS)-induced mitochondrial abnormalities may have important consequences in the pathogenesis of degenerative diseases and cancer. Vitamin C is an important antioxidant known to quench ROS, but its mitochondrial transport and functions...
Physician adoption of hyperbaric oxygen therapy in the treatment of chronic wounds.
Abstract: Hyperbaric oxygen therapy, a treatment alternative for chronic wounds, has been used for several decades yet little is known about factors that influence physicians to incorporate this therapy into practice. To assess wound care physician knowledge of,...
Hyperbaric oxygen therapy: a meeting place for medicine and dentistry.
Abstract: The hyperbaric medicine facility at Hennepin County Medical Center has been serving patients from throughout the region for more than 40 years. Some of these patients have head and neck cancer and are suffering delayed complications of radiation therapy....
An adolescent scuba diver with 2 episodes of diving-related injuries requiring hyperbaric oxygen recompression therapy: a case report with medical considerations for child and adolescent scuba divers.
Abstract: Worldwide, more than 1000 scuba (self-contained underwater breathing apparatus) diving injuries per year requiring hyperbaric recompression are documented. Approximately 80 to 90 fatalities per year are reported in North America. On average, there were 16...
Involvement of the mitochondrial ATP-sensitive potassium channel in the neuroprotective effect of hyperbaric oxygenation after cerebral ischemia.
Abstract: In the present study, we investigated whether activation of mitochondrial ATP-sensitive potassium channel is involved in the neuroprotective effect offered by early hyperbaric oxygenation after cerebral ischemia. The selective mitochondrial ATP-sensitive...
Evaluation of diabetic wound classifications and a new wound score.
Abstract: We review seven classification systems for foot wounds in patients with diabetes and evaluate them in a table format based on 10 criteria judged to be the most important for assessing their effectiveness. Criteria include such factors as objectivity,...
Delayed and multiple hyperbaric oxygen treatments expand therapeutic window in rat focal cerebral ischemic model.
Abstract: Although the brain-protective effect of single, early applications of hyperbaric oxygen (HBO) has been reported in acute ischemic stroke models, few studies have reported the long-term effect--especially after multiple HBO applications. This study employed...