Topical oxygen as an adjunct to wound healing: a clinical case series.
Abstract: BACKGROUND: Disrupted vasculature and high energy-demand to support processing and regeneration of wounded tissue are typical characteristics of a wound site. Oxygen delivery is a critical element for the healing of wounds. Clinical experience with...
How to overcome (and exploit) tumor hypoxia for targeted gene therapy.
Abstract: Tumor hypoxia has long been recognized as a critical issue in oncology. Resistance of hypoxic areas has been shown to affect treatment outcome after radiation, chemotherapy, and surgery in a number of tumor sites. Two main strategies to overcome tumor...
Anaestethic problems in Sanfilippo syndrome. A rare case of adult patient.
Abstract: The authors report the case of a female patient (41 years old) affected by mucopolysaccharidosis type III or Sanfilippo syndrome submitted to a gynecologic surgical procedure and describe the main anesthesiologic problems. A sub-arachnoid anesthesia with...
Hyperbaric oxygen treatment of hemorrhagic radiation-induced gastritis after esophagectomy.
Abstract: My colleagues and I present 2 cases of hemorrhagic postesophagectomy gastritis after chemoradiotherapy for esophageal cancer. On the basis of the location of the gastritis (lesser curve and midstomach) and the classic radiation injury appearance, radiation...
Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages
Abstract Hyperbaric oxygen (HBO) is 100% oxygen administered at elevated atmospheric pressure to patients with inflammatory diseases. We developed an in vitro model to investigate the effects of HBO on stimulus-induced proinflammatory cytokine transcription and...
[Hyperbaric oxygen treatment for children with cerebral palsy].
Abstract: Demand from parents has made hyperbaric oxygenation (HO) inhalation the most popular and rapid growing therapy for children with cerebral palsy (CP). To review peer reviewed articles of HO in children with CP to determine its efficacy and risks, literature...
[CO2 pneumoperitoneum inhibits in vitro proliferation of human carcinoma cells].
Abstract: Up to this day, the influence of laparoscopy and hyperbaric carbon dioxide on the growth of tumor cells is not yet clear. Cells of human colonic carcinoma CX-2 and pancreatic carcinoma DAN-G were exposed to carbon dioxide under pressures of zero, 6 and 12...
Protective effects of alpha-tocopherol and mannitol in both circulatory shock and cerebral ischaemia injury in rat heatstroke.
Abstract: 1. There is evidence that hydroxyl radicals are accumulated and oxidative stress is produced in multiple organs, including the brain, of rats with heat stroke. Herein, we investigated the effect on heat stroke-induced circulatory shock and cerebral ischaemic...
Intractable livedoid vasculopathy successfully treated with hyperbaric oxygen.
Abstract: We describe a new method for treating livedoid vasculopathy. The typical presentation of livedoid vasculopathy includes chronic, recurrent painful ulcers, satellite scar-like atrophy and telangiectasia involving the lower extremities. Histologically, these...