Neonatal necrotizing fasciitis: a report of three cases and review of the literature.
Abstract: Necrotizing fasciitis (NF) is a predominantly adult disorder, with bacterial infection of the soft tissue. In children, it is relatively rare and has a fulminant course with a high mortality rate. In the neonate, most cases of NF are attributable to...
Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial.
Abstract: To assess neurological sequelae in patients with all grades of carbon monoxide (CO) poisoning after treatment with hyperbaric oxygen (HBO) and normobaric oxygen (NBO). Randomised controlled double-blind trial, including an extended series of...
TP53 overexpression in radiation-induced osteosarcoma of the rabbit mandible.
Abstract: The objective of this study was to investigate the incidence of overexpression of TP53 (formerly known as p53) in osteosarcomas occurring after treatment of rabbit mandibles with high-dose external-beam radiation. As part of a protocol investigating...
[Changes in autonomic regulation in patients with multiple sclerosis during hyperbaric oxygenation].
Abstract: Our objective in this study was to determine phase transitions of bodily vegetative reactivity in different baseline functional states in patients with multiple sclerosis (MS) during the stages of the hyperbaric oxygen (HBO) procedures. The developed...
A review of the Marx protocols: prevention and management of osteoradionecrosis by combining surgery and hyperbaric oxygen therapy.
Abstract: The 30/10 protocol is employed in the treatment of established osteoradionecrosis. No surgery should be attempted before the first 30 HBO treatments have provided sufficient angiogenesis to support surgical wounding. After 30 treatments surgical management...
Hyperbaric oxygen therapy for perineal Crohn’s disease.
Abstract: Perineal lesions are a frequent and troublesome complication of Crohn's disease. Although there are various surgical and medical therapeutic regimens available to treat these lesions, all have significant associated morbidity, mortality, and toxicity....
Assessment of the level of sensory block after subarachnoid anesthesia using a pressure palpator.
Abstract: In a cross-over study, we compared two methods of assessing the level of sensory block during subarachnoid anesthesia: the traditional pinprick sensation or a novel pressure palpator exerting a pressure of 650 g. Fifty patients scheduled for transurethral...
The incidence of transient radicular irritation after spinal anesthesia in obstetric patients.
Abstract: Transient radicular irritation (TRI) has been described after spinal anesthesia, particularly with 5% hyperbaric spinal lidocaine. The purpose of this study was to determine the incidence of TRI in obstetric patients. All obstetric patients undergoing spinal...
Targeting lurking pathogens in acute traumatic and chronic wounds.
Abstract: The appropriate antimicrobial treatment for skin and soft tissue following acute trauma is determined by the mechanism of injury, time from injury to treatment, environmental wound contamination, pathogenicity of colonizing bacteria, and patient-specific...