Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients
Abstract Vascular dysfunction is entwined with aging and in the pathogenesis of Alzheimer's disease (AD) and contributes to reduced cerebral blood flow (CBF) and consequently, hypoxia. Hyperbaric oxygen therapy (HBOT) is in clinical use for a wide range of medical...
Effects of Neurofeedback on Fibromyalgia: A Randomized Controlled Trial
Abstract Background: Fibromyalgia is a chronic widespread pain condition that is associated with sleep disturbances and cognitive impairments. Neurofeedback has been demonstrated to improve pain, sleep quality, and fatigue. However, few studies have examined the...
The effects of hyperbaric oxygen therapy on neuropathic pain via mitophagy in microglia
Abstract Purpose: Hyperbaric oxygen (HBO) therapy has been suggested to palliate neuropathic pain, but the mechanisms involved are not well understood. This study explored the involvement of microglial mitophagy via HBO relative to neuropathic pain therapy. Materials...
Hyperbaric Oxygenation for Lyme Vasculitis
Purpose It is the purpose of this paper to demonstrate the positive effects of hyperbaric oxygenation on severe encephalopathy occurring in Lyme Disease as a synergistic treatment with antibiotics. Summary Lyme disease is a tick-borne disease caused by a Borrelia...
Integrative Approaches to Treat Migraine Headaches
The past 10 months have been a headache and, in anticipation of the long, trying winter weeks ahead, we are addressing a concern specific to an estimated 20% of the American population: migraine headaches. In fact, because they are often misdiagnosed, the percentage...
Changes in attentional processing following neurofeedback in patients with persistent post-concussive symptoms: a pilot study
Abstract Objective: Persistent post-concussive symptoms (PPCS) often include attention deficits, particularly orienting and executive attention. Research in other clinical populations has demonstrated that neurofeedback therapy (NFT) is effective at improving...
A Randomised Clinical Trial to Compare the Efficacy of Hyperbaric Oxygen Therapy with Neoadjuvant Chemotherapy Carcinoma Breast
Abstract: Hypoxia plays a major role in cell survival, angiogenesis, glycolytic metabolism and metastasis in breast cancer. Hyperbaric oxygen therapy (HBOT) has a well-established effect for attenuating the effects of hypoxia by enhancing the effects of chemotherapy...
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial
Abstract Introduction: Aging is characterized by the progressive loss of physiological capacity. At the cellular level, two key hallmarks of the aging process include telomere length (TL) shortening and cellular senescence. Repeated intermittent hyperoxic exposures,...
Overview of the Immune System
Function The overall function of the immune system is to prevent or limit infection. An example of this principle is found in immune-compromised people, including those with genetic immune disorders, immune-debilitating infections like HIV, and even pregnant women,...