Superoxide Dismutase and Hyperbaric Oxygen Therapy of the Patient with Rheumatoid Arthritis
Cu, Zn-SOD values were measured by enzyme immunoassay in the synovial fluid, leukocytes in the synovial fluid, synovial membrane, and leukocytes in blood of the patients with rheumatoid arthritis. SOD activity, lipoperoxide value in serum, ESR, and Lansbury’s index of the patients with rheumatoid arthritis under hyperbaric oxygen (HBO) therapy were also investigated. SOD values of synovial fluid and of leukocytes in synovial fluid from rheumatoid arthritis group were found to be higher than those from osteoarthritis group. No significant difference was found the SOD values in leukocytes of blood and synovial membrane between two groups. In the patients with rheumatoid arthritis under HBO therapy the SOD activity was increased, whereas lipoperoxide values was decreased.
Hyperbaric oxygen for multiple sclerosis.
Abstract: Neubauer, , , , , , , , (1985). Hyperbaric oxygen for multiple sclerosis. Lancet (London, England), 1985 Apr;1(8432):810-1. https://www.ncbi.nlm.nih.gov/pubmed/2858678
Eighth annual Juan del Regato lecture. Chemical modifiers of radiosensitivity–theory and reality: a review.
Abstract: In this review the poor clinical gains from hyperbaric oxygen (HBO) and misonidazole (MISO) are discussed critically. The biggest factor reducing clinical gains is almost certainly reoxygenation. Other possible reasons include vasoconstrictive...
Hyperbaric oxygen and multiple sclerosis.
Abstract: Letter to the Editor (1985). Hyperbaric oxygen and multiple sclerosis. Lancet (London, England), 1985 Mar;1(8428):572-3. https://www.ncbi.nlm.nih.gov/pubmed/2857914
Metastatic nontraumatic Clostridium septicum osteomyelitis.
Abstract: Nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. We believe that this is the first reported case of metastatic nontraumatic Clostridium septicum osteomyelitis. Early...
New aspects on the pathophysiology of wound infection and wound healing–the problem of lowered oxygen pressure in the tissue.
Abstract: There is a correlation between tissue oxygen tension, incidence of infection and disturbance of wound healing. Scientific investigations in recent years have documented that infection and tissue repair are processes consuming oxygen. Animal experiments have...
Hyperbaric oxygen and multiple sclerosis: short-term results of a placebo-controlled, double-blind trial.
In a study of 120 patients with chronic multiple sclerosis the effects of treatment with 100% oxygen at 2 atmospheres absolute for 90 min daily for a total of 20 exposures were compared with those of normal air at normal pressure for a similar length of time within the same compression chamber. No patient in either group showed any improvement on the Kurtzke disability status scale. 12 of 51 patients in the hyperbaric-oxygen group and 3 of 47 control patients improved on the Kurtzke functional systems scale on the subjective bowel/bladder parameter only. Such a degree of improvement can also be achieved with medication for urinary symptoms, but none of the patients in this study received such medication. The short-term results of this trial do not support the claims made for hyperbaric oxygen in the management of multiple sclerosis.
Cerebral air embolism resulting from invasive medical procedures. Treatment with hyperbaric oxygen.
Abstract: The introduction of air into the venous or arterial circulation can cause cerebral air embolism, leading to severe neurological deficit or death. Air injected into the arterial circulation may have direct access to the cerebral circulation. A patent foramen...
[Hyperbaric oxygen therapy of anaerobic brain abscesses following tonsillectomy].
Abstract: This study describes the clinical course of a 31 year old woman who developed multiple anaerobic brain abscesses six days after tonsillectomy, followed by hemoparesis and dysarthria. In spite of craniotomy, repeated punctures and drainage of pus and high...