Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial.

Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism. 62 children with autism recruited from 6 centers, ages 2-7 years (mean 4.92 +/- 1.21), were randomly assigned to 40 hourly treatments of either hyperbaric treatment at 1.3 atmosphere (atm) and 24% oxygen (“treatment group”, n = 33) or slightly pressurized room air at 1.03 atm and 21% oxygen (“control group”, n = 29). Outcome measures included Clinical Global Impression (CGI) scale, Aberrant Behavior Checklist (ABC), and Autism Treatment Evaluation Checklist (ATEC).

[Influence of hyperbaric oxygen treatment on neural plasticity in experimental rats].

Abstract: To explore the influence of hyperbaric oxygen (HBO) treatment on neural plasticity and it's mechanism in experimental rats with cerebral ischemia. Ninety-healthy male adult Sprague-Dawley rats (3 to approximately 4 month old) were randomly divided into a...

Treatment of diabetic foot infection with hyperbaric oxygen therapy.

Abstract: This study was performed to evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of the infected diabetic foot. Forty-two patients with 44 infected diabetic feet receiving HBOT were divided into two groups. One group of 21 patients...

Risk factors and treatment outcome in scuba divers with spinal cord decompression sickness.

Abstract: This study was designed to determine the recompression strategy and the potential risk factors associated with the development of severe diving-related spinal cord decompression sickness (DCS). Sixty-three injured recreational divers (52 men and 11 women; 46...

[New development in bisphosphonate treatment. Bisphosphonate therapy and osteonecrosis of the jaws].

Abstract: Bisphosphonates (BP) have clinically been used as a highly effective drug in the treatment of hypercalcemia of malignancy, multiple myeloma, skeletal events associated with metastatic breast cancer and prostate cancer, and osteoporosis. Despite these...

Vacuum-assisted closure therapy in the management of head and neck wounds.

Abstract: The wound vacuum-assisted closure (VAC) has been used in many areas of surgery to promote healing and facilitate secondary reconstruction. Until recently, this treatment modality was overlooked in the otolaryngology literature, and the authors propose that...

Hyperbaric oxygen preconditioning improves myocardial function, reduces length of intensive care stay, and limits complications post coronary artery bypass graft surgery.

Abstract: The objective of this study was to determine whether preconditioning coronary artery disease (CAD) patients with HBO(2) prior to first-time elective on-pump cardiopulmonary bypass (CPB) coronary artery bypass graft surgery (CABG) leads to improved myocardial...

Hyperbaric oxygen preconditioning improves myocardial function, reduces length of intensive care stay, and limits complications post coronary artery bypass graft surgery.

Abstract: The objective of this study was to determine whether preconditioning coronary artery disease (CAD) patients with HBO(2) prior to first-time elective on-pump cardiopulmonary bypass (CPB) coronary artery bypass graft surgery (CABG) leads to improved myocardial...

[Continuous spinal block in a patient undergoing partial gastrectomy: case report].

Abstract: Due to the high incidence of technical and neurological complications, continuous spinal blocks were not performed for several years. With the advent of intermediate catheters the technique has been used more often and gaining acceptance among...

HBOT Research