Nutritional IV Therapy

What is Nutritional IV Therapy?

IV nutrient therapy is the most effective way of getting vitamins, minerals, and amino acids straight into the bloodstream. When given intravenously, the blood achieves concentrations not obtainable with taking them by mouth. There is 100% bio-availability to cells without the stomach upset or absorption issues. We offer several nutritional intravenous (IV) therapies that have incredible benefits for your healing.

Our IV’s have been shown to aid in the healing process of many conditions such as neurological disease, cardiovascular disease, joint and muscle pain and many more. They also have proven benefits for general health and wellness (1-5)! The contents of IV’s are supplied directly to the blood stream, significantly reducing the loss of any of the vitamins and minerals during digestion that often occurs with oral supplements. Therefore, your body end up absorbing more of the vitamins and minerals and at a quicker rate. You can read more about the specific benefits of each IV therapy below.

Benefits of IV Nutrient Therapies:

  • Boost Energy
  • Boost Immunity & Treat Autoimmunity
  • Decrease Pain & Inflammation
  • Detoxification
  • Improve Brain Function & Mental Clarity
  • Relieve Stress & Anxiety
  • Cold & Flu Remedy
  • Support Athletic Performance & Recovery
  • Hydration
  • Migraine Relief
  • Improve Overall Well-being

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    Nutritional IV Packages

    How can I get IV therapy / become a patient?

    • If you are an active Extivita patient receiving hyperbaric treatments, simply consult with our provider (this is at no charge to you).
    • If you are not currently a patient and only wish to receive IV therapy, you must first have an office visit with our provider. We might require certain labs from you prior to receiving certain IV therapies.  Please call 919-354-3775 or fill out the contact form below to schedule a visit.

    Recent IV Therapy News & Research

    1. Nielsen, Forrest H. “Effects of Magnesium Depletion on Inflammation in Chronic Disease.” Current Opinion in Clinical Nutrition and Metabolic Care, vol. 17, no. 6, Nov. 2014, pp. 525–30. PubMed, doi:10.1097/MCO.0000000000000093.
    2. Kennedy, David O., et al. “Effects of High-Dose B Vitamin Complex with Vitamin C and Minerals on Subjective Mood and Performance in Healthy Males.” Psychopharmacology, vol. 211, no. 1, July 2010, pp. 55–68. PubMed Central, doi:10.1007/s00213-010-1870-3.
    3. Lewis, John E., et al. “The Effect of Methylated Vitamin B Complex on Depressive and Anxiety Symptoms and Quality of Life in Adults with Depression.” ISRN Psychiatry, vol. 2013, Jan. 2013. PubMed Central, doi:10.1155/2013/621453.
    4. Goodwin, J. S., et al. “Association between Nutritional Status and Cognitive Functioning in a Healthy Elderly Population.” JAMA, vol. 249, no. 21, June 1983, pp. 2917–21.
    5. Franco, R., et al. “The Central Role of Glutathione in the Pathophysiology of Human Diseases.” Archives of Physiology & Biochemistry, vol. 113, no. 4/5, Taylor & Francis Ltd, Oct. 2007, pp. 234–58. EBSCOhost, doi:10.1080/13813450701661198.
    6. Wang, Fong, et al. “Oral Magnesium Oxide Prophylaxis of Frequent Migrainous Headache in Children: A Randomized, Double-Blind, Placebo-Controlled Trial.” Headache, vol. 43, no. 6, June 2003, pp. 601–10. PubMed, doi:10.1046/j.1526-4610.2003.03102.x.
    7. von Luckner, Alexander, and Franz Riederer. “Magnesium in Migraine Prophylaxis—Is There an Evidence‐Based Rationale? A Systematic Review.” Headache: The Journal of Head and Face Pain, vol. 58, no. 2, Wiley Subscription Services, Inc, 2018, pp. 199–209., doi:10.1111/head.13217.
    8. Office of Dietary Supplements – Calcium. Accessed 18 Aug. 2020.
    9. Tarleton, Emily K., and Benjamin Littenberg. “Magnesium Intake and Depression in Adults.” Journal of the American Board of Family Medicine: JABFM, vol. 28, no. 2, Apr. 2015, pp. 249–56. PubMed, doi:10.3122/jabfm.2015.02.140176.
    10. Rajizadeh, Afsaneh, et al. “Effect of Magnesium Supplementation on Depression Status in Depressed Patients with Magnesium Deficiency: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrition, vol. 35, Elsevier BV, Elsevier Inc, Elsevier BV, Elsevier Limited, 2017, pp. 56–60., doi:10.1016/j.nut.2016.10.014.
    11. Saedisomeolia, Ahmad, and Marziyeh Ashoori. “Riboflavin in Human Health: A Review of Current Evidences.” Advances in Food and Nutrition Research, vol. 83, 2018, pp. 57–81. PubMed, doi:10.1016/bs.afnr.2017.11.002.
    12. Kennedy, David. “B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review.” Nutrients, vol. 8, no. 2, MDPI AG, MDPI, 2016, pp. 68–68., doi:10.3390/nu8020068.
    13. O’Leary, Fiona, and Samir Samman. “Vitamin B12 in Health and Disease.” Nutrients, vol. 2, no. 3, Mar. 2010, pp. 299–316. PubMed Central, doi:10.3390/nu2030299.
    14. Braidy, Nady et al. “Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.” Antioxidants & redox signaling vol. 30,2 (2019): 251-294. doi:10.1089/ars.2017.7269
    15. Yoshino, Jun, et al. “NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.” Cell Metabolism, vol. 27, no. 3, Mar. 2018, pp. 513–28. PubMed, doi:10.1016/j.cmet.2017.11.002. 
    16. Camacho-Pereira, Juliana, et al. “CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.” Cell Metabolism, vol. 23, no. 6, June 2016, pp. 1127–39. PubMed, doi:10.1016/j.cmet.2016.05.006. 
    17. Imai, Shin-ichiro, and Leonard Guarente. “NAD+ and Sirtuins in Aging and Disease.” Trends in Cell Biology, vol. 24, no. 8, Aug. 2014, pp. 464–71. PubMed, doi:10.1016/j.tcb.2014.04.002. 
    18. Hikosaka, Keisuke, et al. “Deficiency of Nicotinamide Mononucleotide Adenylyltransferase 3 (Nmnat3) Causes Hemolytic Anemia by Altering the Glycolytic Flow in Mature Erythrocytes.” The Journal of Biological Chemistry, vol. 289, no. 21, May 2014, pp. 14796–811. PubMed, doi:10.1074/jbc.M114.554378. 
    19. Fang, Evandro F., et al. “NAD+ in Aging: Molecular Mechanisms and Translational Implications.” Trends in Molecular Medicine, vol. 23, no. 10, Oct. 2017, pp. 899–916. PubMed, doi:10.1016/j.molmed.2017.08.001. 
    20. Lutz, Mirjam I., et al. “Distinct Patterns of Sirtuin Expression during Progression of Alzheimer’s Disease.” Neuromolecular Medicine, vol. 16, no. 2, June 2014, pp. 405–14. PubMed, doi:10.1007/s12017-014-8288-8. 
    21. Qin, Weiping, et al. “Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction.” The Journal of Biological Chemistry, vol. 281, no. 31, Aug. 2006, pp. 21745–54. PubMed, doi:10.1074/jbc.M602909200. 
    22. Brandes, Ralf P. “Activating SIRT1: A New Strategy to Prevent Atherosclerosis?” Cardiovascular Research, vol. 80, no. 2, Nov. 2008, pp. 163–64. PubMed, doi:10.1093/cvr/cvn245. 
    23. Yu, Wei, et al. “SIRT1: A Novel Target to Prevent Atherosclerosis.” Journal of Cellular Biochemistry, vol. 108, no. 1, Sept. 2009, pp. 10–13. PubMed, doi:10.1002/jcb.22240. 
    24. de Picciotto, Natalie E., et al. “Nicotinamide Mononucleotide Supplementation Reverses Vascular Dysfunction and Oxidative Stress with Aging in Mice.” Aging Cell, vol. 15, no. 3, June 2016, pp. 522–30. PubMed, doi:10.1111/acel.12461.
    25. Miller, R et al. “COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity.” Medical hypotheses vol. 144 (2020): 110044. doi:10.1016/j.mehy.2020.110044
    26. Pfluger, Paul T., et al. “Sirt1 Protects against High-Fat Diet-Induced Metabolic Damage.” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 28, July 2008, pp. 9793–98. PubMed, doi:10.1073/pnas.0802917105.
    27. Johnson, Sean, and Shin-ichiro Imai. “NAD + Biosynthesis, Aging, and Disease.” F1000Research, vol. 7, Feb. 2018. PubMed Central, doi:10.12688/f1000research.12120.1.
    28. Grant, Ross et al. “A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD.” Frontiers in aging neuroscience vol. 11 257. 12 Sep. 2019, doi:10.3389/fnagi.2019.00257
    29. Deponte, Marcel. “The Incomplete Glutathione Puzzle: Just Guessing at Numbers and Figures?” Antioxidants & Redox Signaling, vol. 27, no. 15, Nov. 2017, pp. 1130–61. PubMed Central, doi:10.1089/ars.2017.7123.
    30. Alpert, Michelle. “The Diverse Benefits of Glutathione: A Key Antioxidant for Reversing Chronic Illness.” Alternative and Complementary Therapies, vol. 11, no. 5, Oct. 2005, pp. 241–45. (Crossref), doi:10.1089/act.2005.11.241.
    31. Pizzorno, Joseph. “Glutathione!” Integrative Medicine: A Clinician’s Journal, vol. 13, no. 1, Feb. 2014, pp. 8–12.
    32. Sadeghi, Omid, et al. “Effects of Pyridoxine Supplementation on Severity, Frequency and Duration of Migraine Attacks in Migraine Patients with Aura: A Double-Blind Randomized Clinical Trial Study in Iran.” Iranian Journal of Neurology, vol. 14, no. 2, Apr. 2015, pp. 74–80.
    33. Ishmael, Faoud T. “The Inflammatory Response in the Pathogenesis of Asthma.” The Journal of the American Osteopathic Association, vol. 111, no. 11_suppl_7, American Osteopathic Association, Nov. 2011, pp. S11–17.
    34. Hemilä, Harri. “Vitamin C and Asthma.” Journal of Allergy and Clinical Immunology, vol. 134, no. 5, Elsevier, Nov. 2014, p. 1216., doi:10.1016/j.jaci.2014.08.032.
    35. Moreno-Macias, Hortensia, and Isabelle Romieu. “Effects of Antioxidant Supplements and Nutrients on Patients with Asthma and Allergies.” Journal of Allergy and Clinical Immunology, vol. 133, no. 5, May 2014, pp. 1237–44. (Crossref), doi:10.1016/j.jaci.2014.03.020.
    36. Wood, Lisa G., et al. “Manipulating Antioxidant Intake in Asthma: A Randomized Controlled Trial.” The American Journal of Clinical Nutrition, vol. 96, no. 3, Oxford Academic, Sept. 2012, pp. 534–43., doi:10.3945/ajcn.111.032623.
    37. Statovci, Donjete, et al. “The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces.” Frontiers in Immunology, vol. 8, Frontiers, 2017. Frontiers, doi:10.3389/fimmu.2017.00838.
    38. Thuesen, B. H., et al. “Atopy, Asthma, and Lung Function in Relation to Folate and Vitamin B(12) in Adults.” Allergy, vol. 65, no. 11, Nov. 2010, pp. 1446–54. PubMed, doi:10.1111/j.1398-9995.2010.02378.x.
    39. Shrader, Welman A. “Short and Long Term Treatment of Asthma with Intravenous Nutrients.” Nutrition Journal, vol. 3, May 2004, p. 6. PubMed Central, doi:10.1186/1475-2891-3-6.
    40. Popa, Calin, et al. “The Role of TNF-Alpha in Chronic Inflammatory Conditions, Intermediary Metabolism, and Cardiovascular Risk.” Journal of Lipid Research, vol. 48, no. 4, Apr. 2007, pp. 751–62. PubMed, doi:10.1194/jlr.R600021-JLR200.
    41. Ellis, Mary. “Intravenous Rehydration | Definition and Patient Education.” Healthline, 17 Sept. 2018,