Abstract: Chronic pain is one of the frequently encountered clinical problems that is difficult to cure. Hyperbaric oxygen (HBO) therapy has been reported in chronic pain syndromes with promising results. In this review, we focus on the effectiveness of HBO in...
HBOT Research
Explore our database on Hyperbaric Oxygen Therapy (HBOT) Research below.
Extivita maintains an extensive research & publication database for various diseases and therapies such as Hyperbaric Oxygen Therapy, Neurofeedback, Nutritional IV Therapy, Infrared Sauna, and Pulsed Electromagnetic Field Therapy.
For a complete list of indications treated at Extivita, explore the conditions we treat.
Oxygen therapy in permanent brain ischemia: potential and limitations.
Abstract: Both normobaric (NBO) and hyperbaric (HBO) oxygen therapy are protective in transient cerebral ischemia. In contrast, in permanent ischemia models, which reflect the majority of clinical strokes, the effectiveness of NBO is unknown, and the effectiveness of...
The effect of acute psychologic stress on systemic and rectal mucosal measures of inflammation in ulcerative colitis
Abstract Background & aims:ย Recent studies suggest that life events and chronic stress increase the risk of relapse in inflammatory bowel disease. Our aim was to study the effects of acute psychologic stress on systemic and rectal mucosal inflammatory responses in...
Counterpoint: hyperbaric oxygen for diabetic foot wounds is not effective.
Abstract: Diabetic foot ulceration is common, affecting 1.0%-4.1% of diabetic persons per year and up to 25% in a lifetime. Diabetic foot ulcers are multifactorial in origin, and many are slow to heal and/or are complicated by infection, frequently leading to...
Preconditioning with hyperbaric oxygen induces tolerance against oxidative injury via increased expression of heme oxygenase-1 in primary cultured spinal cord neurons.
Abstract: Hyperbaric oxygen (HBO) preconditioning can induce ischemic tolerance in the spinal cord. The effect can be attenuated by the administration of an oxygen free radical scavenger or by inhibition of antioxidant enzymes. However, the mechanism underlying HBO...
Clinical observation: Beau’s lines on fingernails after deep saturation dives.
Abstract: Transverse furrows, or Beau's lines, were noted in the fingernails of all 6 divers following a deep saturation dive to apressure equal to 1100 feet (335 meters) ofsea water (3,370 kPa), and in 2 of6 divers following a similar dive to 1000 feet (305 meters)...
Clinical observation: Beau’s lines on fingernails after deep saturation dives.
Abstract: Transverse furrows, or Beau's lines, were noted in the fingernails of all 6 divers following a deep saturation dive to apressure equal to 1100 feet (335 meters) ofsea water (3,370 kPa), and in 2 of6 divers following a similar dive to 1000 feet (305 meters)...
A pilot study with long term follow up of hyperbaric oxygen pretreatment in patients with locally advanced breast cancer undergoing neo-adjuvant chemotherapy.
Abstract: Work in an animal cancer model suggests that pretreatment with hyperbaric oxygen can improve tumor vascularity rendering chemotherapy more effective. Accordingly 32 subjects with locally advanced breast carcinoma (>5cm diameter) entered into a randomized...
Effects of hyperbaric oxygen on inflammatory response to wound and trauma: possible mechanism of action.
Abstract: There is growing interest in expanding the clinical applications for HBO2 (hyperbaric oxygen therapy) into new medical and surgical fields. The pathophysiology of response towards wounds, infection, trauma, or surgery involves various chemical mediators that...

