Ulcerative Colitis (UC)
Ulcerative colitis (UC) is an autoimmune inflammatory bowel disease (IBD) characterized by chronic inflammation of the lining of the colon and/or rectum(1). UC is known to involve three main issues: low levels of oxygen in intestinal tissue (hypoxia), increased activity of pro-inflammatory marker T17, and issues with gut flora(2,3,4). These issues result in intestinal sores and ulcers, as well as bloody stool, abdominal pain, fatigue, diarrhea and weight loss (5). Typical treatment starts with 5-aminosalicylic acid, and progresses to corticosteroids, immunomodulators, TNF-inhibitors, and/or colectomy if symptoms persist. These treatments all have adverse side effects, some of which are very severe (5).
Extivita Therapies for Ulcerative Colitis: