Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised with ulcerations. Inflammatory bowel diseases (ulcerative colitis and Crohn’s disease) and haematologic diseases (leukaemia, preleukaemia and monoclonal gammopathy) have been reported in about 40-50% of PG patients in whom the treatment of the underlying disease is important for the improvement of the lesions. We herein report a colorectal adenocarcinoma patient with PG, who responded partially to topical treatments and systemic immunosuppressants and healed completely with the aid of surgical wound repair and hyperbaric oxygen therapy.
Altunay, Kucukunal, Sarikaya, Tukenmez Demirci (2014). A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum. International wound journal, 2014 Aug;11(4):350-3. https://www.ncbi.nlm.nih.gov/pubmed/23106966