Abstract: Little is known about the impact of hyperbaric oxygen treatment (HBOT) on matrix metalloproteinase (MMP) production in pre-existing high-oxidant wounds. This study aimed to investigate whether HBOT modulates reactive oxygen species (ROS) and MMP regulation...
Cancer
Hyperbaric Oxygen Therapy (HBOT) Research for Cancer.
SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain.
Abstract: Our previous studies have shown that hyperbaric oxygen preconditioning (HBO-PC) induces tolerance to cerebral ischemia/reperfusion (I/R). This study aimed to investigate whether SirT1, a class III histone deacetylase, is involved in neuroprotection elicited...
The influence of radiation therapy on dental implantology.
Abstract: Patients with a history of head and neck cancer resection require extensive prosthodontic rehabilitation following cancer treatment. The oral anatomy drastically changes from ablative therapy, and the oral tissue response becomes altered as a consequence of...
A retrospective study of outcomes in subjects of head and neck cancer treated with hyperbaric oxygen therapy for radiation induced osteoradionecrosis of mandible at a tertiary care centre: an Indian experience.
Abstract: Osteoradionecrosis (ORN) of the mandible is a rare complication of radiation therapy for head and neck cancer. It manifests as an area of exposed necrotic bone failing to heal for at least 3 months. Our study aims to determine the effectiveness of HBO in...
Management of dental complications in a child with rhabdomyosarcoma.
Abstract: Radiotherapy treatment options can cause adverse dental sequelae, including xerostomia, dental radiation caries, abnormal tooth development, and osteoradionecrosis (ORN). Hyperbaric oxygen (HBO) therapy can be used prophylactically or therapeutically to...
Limited evidence to demonstrate that the use of hyperbaric oxygen (HBO) therapy reduces the incidence of osteoradionecrosis in irradiated patients requiring tooth extraction.
Abstract: The search covered Medline from January 1948 through March 2008. The subject search by the authors used the following key phrases: Prophylactic hyperbaric oxygen (HBO); preventing osteoradionecrosis (ORN); HBO; ORN; HBO and ORN; HBO, ORN, and dental...
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.
Abstract: Abnormal cancer metabolism creates a glycolytic-dependency which can be exploited by lowering glucose availability to the tumor. The ketogenic diet (KD) is a low carbohydrate, high fat diet which decreases blood glucose and elevates blood ketones and has...
Hyperbaric oxygen and cancer: more complex than we expected.
Abstract: Wenwu, Xuejun, Hengyi, Kan, , , , , (2013). Hyperbaric oxygen and cancer: more complex than we expected. Targeted oncology, 2013 Jun;8(2):79-81. https://www.ncbi.nlm.nih.gov/pubmed/23345035
Hyperbaric oxygen therapy in rats attenuates ischemia-reperfusion testicular injury through blockade of oxidative stress, suppression of inflammation, and reduction of nitric oxide formation.
Abstract: To evaluate the therapeutic utility of hyperbaric oxygen (HBO) therapy on testicular ischemia/reperfusion (I/R) injury and elucidate the underlying molecular mechanism, we tested whether HBO therapy provided rescue of the testes after torsion in rats....