Abstract: 1. The distribution of an anti-cancer agent carboplatin to brains was investigated in combination with hyperbaric oxygenation treatment in rats. 2. After intravenous administration of carboplatin (30 mg kg(-1)) to male Wistar rats, elimination curves of...
Cancer
Hyperbaric Oxygen Therapy (HBOT) Research for Cancer.
Initial experience with bevacizumab treatment for biopsy confirmed cerebral radiation necrosis.
Abstract: Cerebral radiation necrosis is a serious complication of radiation treatment for brain tumors. Therapeutic options include corticosteroids, anticoagulation and hyperbaric oxygen with limited efficacy. Bevacizumab, an antibody against VEGF had been reported...
The role of hyperbaric oxygen therapy (hot) as an otoprotection agent against cisplatin ototoxicity.
Abstract: Hyperbaric oxygen therapy (HOT) consists of intermittent inhalations of 100% oxygen at a pressure higher than 1 atm. It is an important adjuvant therapy in pathological processes like soft tissue infections, radiation injury, gas gangrene, osteomyelitis and...
Increased transendothelial permeability of anti-cancer agent carboplatin with the aid of hyperbaric oxygenation.
Abstract: 1. The objective was to investigate the transport of an anticancer agent carboplatin across the blood-brain barrier in combination with hyperbaric oxygenation treatment. An in vitro well-validated model of bovine brain capillary endothelial cells was used....
Implant-retained nasal prosthesis for reconstruction of large rhinectomy defects: the Salisbury experience.
Abstract: The authors report their experience with 34 patients who had large full thickness nasal defects reconstructed with an implant-retained prosthesis. Their technique of modifying post-rhinectomy defects is described and factors influencing implant success are...
Side effect of head and neck radiotherapy: optic neuropathy.
Abstract: Therapeutic irradiation of the head and neck region for control of tumor growth and for palliation of tumor mass effect, as well as stereotactic surgery increased in use in recent years, having a wide applicability. Despite technological advances,...
The duration of intrathecal bupivacaine mixed with lidocaine.
Abstract: Although spinal bupivacaine may have too long duration to be useful in the ambulatory setting, recent animal data suggest that lidocaine added to spinal bupivacaine may reduce the duration of bupivacaine spinal anesthesia. We explored whether lidocaine added...
Hyperbaric oxygen therapy for late radiation tissue injury in gynaecological patients.
Abstract: Pelvic radiation therapy is an important element of curative therapy for gynaecological cancers. Serious radiation-related complications developing months or years after treatment are known as late radiation tissue injury (LRTI). We investigated the possible...
Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a randomized trial in oropharyngeal and nasopharyngeal cancer.
Abstract: Comparison of quality of life (QoL) and side effects in a randomized trial for early hyperbaric oxygen therapy (HBOT) after radiotherapy (RT). From 2006, 19 patients with tumor originating from the tonsillar fossa and/or soft palate (15), base of tongue (1),...