Abstract: Hyperglycemia affects approximately one-third of acute ischemic stroke patients and is associated with poor clinical outcomes. In experimental and clinical stroke studies, hyperglycemia has been shown to be detrimental to the penumbral tissue for several...
HBOT Research
Explore our database on Hyperbaric Oxygen Therapy (HBOT) Research below.
Extivita maintains an extensive research & publication database for various diseases and therapies such as Hyperbaric Oxygen Therapy, Neurofeedback, Nutritional IV Therapy, Infrared Sauna, and Pulsed Electromagnetic Field Therapy.
For a complete list of indications treated at Extivita, explore the conditions we treat.
The protective effect of hyperbaric oxygen and Ginkgo biloba extract on Aฮฒ25-35-induced oxidative stress and neuronal apoptosis in rats.
Alzheimer’s disease (AD) is characterized by accumulation and deposition of Aฮฒ peptides in human brains. The present study aimed to determine the protective effect of HBO and EGB761 on Aฮฒ25-35 peptides induced cognitive impairment and neuronal toxicity in rats. Characteristics of AD were induced in rats by the administration of Aฮฒ25-35 in hippocampus. Rats were treated with HBO (2ATA 60min/day), EGB761 (20mg/kg/day), and the combination of HBO+EGB761 (20mg/kg/day+2ATA). The Morris water maze was used to detect the protective effects of HBO and EGB761 against cognitive impairment. The activities of SOD and GSH, the apoptosis-related genes and proteins and the apoptosis rate of hippocampus were detected. Compared to the model group, EGB761 and HBO treatments synergistically improved the escape latency. Furthermore, the activities of SOD and GSH in rat hippocampal tissue were found to have increased with a concomitant reduction in MDA levels, Bax expression, cytochrome c release, and the activity of caspase-9/3.
[Hyperbaric oxygen therapy and inert gases in cerebral ischemia and traumatic brain injury].
Abstract: Cerebral ischemia is a common thread of acute cerebral lesions, whether vascular or traumatic origin. Hyperbaric oxygen (HBO) improves tissue oxygenation and may prevent impairment of reversible lesions. In experimental models of cerebral ischemia or...
Barriers to recruitment for surgical trials in head and neck oncology: a survey of trial investigators.
Abstract: Many randomised trials in surgery suffer from recruitment rates that lag behind projected targets. We aim to identify perceived barriers to recruitment among these pioneering trials in the field of head and neck cancer surgery. Recruiting centres to all...
Changes in nerve microcirculation following peripheral nerve compression
Abstract Following peripheral nerve compression, peripheral nerve microcirculation plays important roles in regulating the nerve microenvironment and neurotrophic substances, supplying blood and oxygen and maintaining neural conduction and axonal transport. This paper...
Does hyperbaric oxygen therapy have the potential to improve salivary gland function in irradiated head and neck cancer patients?
Abstract: Following radiotherapy, many patients with osteoradionecrosis suffer from xerostomia, thereby decreasing their quality of life. Patients can develop problems with speech, eating, increased dental caries, dysphagia, fractured dentition, chronic refractory...
Comments on Margolis et al. Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation.
Abstract: Lรถndahl, Katzman, , , , , , , (2015). Comments on Margolis et al. Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation.ย International wound journal, 2015...
Hyperbaric oxygen therapy provides neuroprotection following spinal cord injury in a rat model.
Abstract: To investigate the effect of hyperbaric oxygen therapy (HBOT) on the iNOS mRNA-iNOS-NO signaling pathway and neurofunction protected in a rat spinal cord injury model. A total of 36 Sprague-Dawley rats were randomly divided into 3 groups: control group...
Combined treatment of methylprednisolone pulse and memantine hydrochloride prompts recovery from neurological dysfunction and cerebral hypoperfusion in carbon monoxide poisoning: a case report.
Abstract: A 49-year-old healthy man developed sudden unconsciousness under inadequate ventilation. Blood gas analysis showed carboxyhemoglobin of 7.3%. After normobaric oxygen therapy, he recovered completely 7 days later. At 3 weeks after carbon monoxide (CO)...

