Berger’s Disease (IgA Nephropathy)
Berger’s disease, clinically referred to as IgA nephropathy, is a specific type of kidney (renal) disease characterized by an antibody (immunoglobulin IgA) build-up in the kidneys. Too much of this antibody reduces the kidneys’ ability to filter wastes in the blood and can cause kidney damage (irreversible scarring) over time. Symptoms include repeated episodes of cola- or tea-colored urine (or blood in the urine), back pain on the sides and below the ribs, swelling in the hands and feet, and high blood pressure. It is estimated that 20 to 40% of adults that have Berger’s Disease for at least 10 to 20 years develop end-stage kidney disease which requires dialysis or a possible kidney transplant.
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Research
[Results of treatments for critical limb ischemia: effectiveness and indications].
Abstract: The treatment of critical limb ischemia (CLI), which is the end stage of arteriosclerosis obliterans and/or Buerger's disease, provides the ischemic tissue with oxygen, and arterial revascularization procedures such as bypass surgery and...
Autologous bone marrow transplantation and hyperbaric oxygen therapy for patients with thromboangiitis obliterans.
Abstract: Many patients suffering from severe ischemic limb disease inevitably experience amputation, despite intensive therapies. Sympathectomy and hyperbaric oxygen therapy are optional therapies for patients with peripheral circulation disorders. Recently, several...
Inflammatory arthritis associated with thromboangiitis obliterans.
Abstract: Thromboangiitis obliterans (TAO) is an uncommon to rare vasculitis of small and medium arteries and veins typically affecting young male smokers. Inflammatory arthritis has only been rarely reported in association with TAO. We describe the case of a young...