Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugular foramen. It is an uncommon condition mainly found in the elderly or in diabetics. To assess the effectiveness of adjunctive hyperbaric oxygen treatment for malignant otitis externa. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 4, 2003), MEDLINE (January 1966 to April 2004) and EMBASE (January 1985 to April 2004) with pre-specified terms. The date of the last search was 5th April 2004. Randomised controlled trials, involving adults, undergoing hyperbaric oxygen therapy in malignant otitis externa.
Phillips, Jones, , , , , , , (2005). Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa. The Cochrane database of systematic reviews, 2005 Apr;(2):CD004617. https://www.ncbi.nlm.nih.gov/pubmed/15846724