Perianal involvement occurs in about 30% of children with Crohn’s disease (CD). Treatment of perianal CD requires a multidisciplinary approach with a combination of immunomodulatory therapy, antibiotics and surgery. Hyperbaric oxygen therapy (HBOT) is a well established treatment to promote tissue healing in different medical conditions. However, HBOT has been seldomly employed for the treatment of perianal CD and its benefits are largely unknown.


Bosa, L., Cananzi, M., Fascetti Leon, F., Gaio, P., Mescoli, C., Mognato, G., Perilongo, G., (2017). Hyperbaric oxygen therapy is an effective adjunctive treatment for severe perianal Crohn’s disease. Digestive and Liver Disease Journal. VOLUME 49, ISSUE 4, SUPPLEMENT , E260-E261, OCTOBER 01, 2017