Patients with nonspecific ulcerative colitis and Crohn’s disease were treated with drug therapy (prednisolone, sulphasalazine, metronidazole per os and hydrocortisone per rectum) and subjected to 12 sessions of HBO. Every 10-14 months the HBO course was repeated. After 7 years of such a treatment a gradual partial recovery of large intestine mucosa and in some cases even its absolute recovery were observed. It was most difficult to get good results when treating lesion of distal colon segments. HBO produced a good effect when the disease was diagnosed at the early stage, when the intestine injury was accompanied by hepatobiliary system disease and in teenagers.
Poliakova, Lukich, Grigor’eva (1991). [Hyperbaric oxygenation and drug therapy in treatment of nonspecific ulcerative colitis and Crohn’s disease]. Fiziologicheskii zhurnal, ;37(5):120-3. https://www.ncbi.nlm.nih.gov/pubmed/1790809