Biochemical parameters (the gaseous composition and acid-base balance of the blood and cerebrospinal fluid (CSF) were investigated in patients with ischemic stroke in the process of hyperbaric oxygenation treatment. A characteristic peculiarity observed was the presence of compensated metabolic acidosis in the CSF which was most expressed in patients with an extensive focus of cerebral infarction. A characteristic change in the venous blood of the brain was the presence of compensated metabolic acidosis. Metabolic acidosis of the cerebral venous blood in patients treated with hyperbaric oxygenation significantly diminished as compared with the control group.

Kaasik, Dmitriev, Tomberg, , , , , , (1988). [Hyperbaric oxygenation in the treatment of patients with ischemic stroke]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988 ;88(9):38-43. https://www.ncbi.nlm.nih.gov/pubmed/3232453