Hyperbaric oxygen (HBO) is an effective adjunct in the management of selected otolaryngologic problems including radiation-induced necrosis of the temporal bone, malignant external otitis, mandibular osteoradionecrosis and refractory osteomyelitis, soft tissue head and necrotizing fasciitis, compromised skin flaps and grafts, acute air or gas embolism, and otologic barotrauma. We describe the management of a patient with insidious Staphylococcus aureus osteomyelitis of the temporal bone by the use of HBO preoperatively and postoperatively in conjunction with surgical debridement. The possible application of angiogenic agents and tetracycline bone-labeling in combination with HBO therapy in the management of refractory neurotologic disease is discussed.

Schweitzer, , , , , , , , (1990). Management of chronic staphylococcal osteomyelitis of the temporal bone: the use of hyperbaric oxygen. Henry Ford Hospital medical journal, 1990 ;38(1):16-20. https://www.ncbi.nlm.nih.gov/pubmed/2228703