Radiation wounds represent some of the most difficult wounds to treat. Historically, there have been few nonsurgical options. Recent research suggests future potential of a therapeutic role for growth factors. Hyperbaric oxygen is currently widely used, but its addition to growth factors may give much greater benefits in the future.
Mustoe, Porras-Reyes, , , , , , , (1993). Modulation of wound healing response in chronic irradiated tissues. Clinics in plastic surgery, 1993 Jul;20(3):465-72. https://www.ncbi.nlm.nih.gov/pubmed/8324985