Hyperbaric oxygen treatment (HBO2) is used commonly for treatment of bone and soft-tissue radiation necrosis. It may be a potential therapy for radiation necrosis seen after brain irradiation. HBO2 risks include generalized tonic-clonic convulsions. We report a patient after resection of anaplastic astrocytoma and 5,580 cGy of total external-beam radiation treatments with brain radiation necrosis who underwent HBO2 therapy and developed a partial seizure during treatment. Mechanisms and implications are discussed.
Doherty, Hampson, , , , , , , (2005). Partial seizure provoked by hyperbaric oxygen therapy: possible mechanisms and implications. Epilepsia, 2005 Jun;46(6):974-6. https://www.ncbi.nlm.nih.gov/pubmed/15946345