A 49-year-old man underwent hyperbaric oxygen (HBO) therapy for the treatment of primary spinal epidural abscess. Although the epidural abscess was initially treated with antibiotic (cefozopran) for 5 days, he subsequently developed motor weakness, paresthesia and urinary retention. MRI demonstrated spinal cord compression at the C1-C4 level. HBO therapy was added to the antibiotic regimen, and three days later we found clinical evidence of a response to treatment. Neurological symptoms were relieved 13 days after HBO therapy. This case suggests that HBO therapy is an effective therapeutic adjunct for the treatment of spinal epidural abscess.

Kohshi, Abe, Mizoguchi, Shimokobe, , , , , (2005). Successful treatment of cervical spinal epidural abscess by combined hyperbaric oxygenation. The Mount Sinai journal of medicine, New York, 2005 Nov;72(6):381-4. https://www.ncbi.nlm.nih.gov/pubmed/16358162