Antioxidant system ceruloplasmin-transferrin (Cp-Tr) and malonic dialdehyde (MDA) concentration changes were studied in the rat serum after the exposure to hyperbaric oxygenation (HBO) at 4 atm for 25 min. 5 sessions of HBO led to an increase in serum MDA concentration. 5 HBO sessions were followed by the activation of Cp-Tr system. Afterwards MDA concentration began to decrease and by the 9th session even reached the initial levels. It is suggested that antioxidant system Cp-Tr takes part in the protection of the organism from toxic oxygen action.

Shinkarenko, Kozlov, Gol’dshteĭn, Azizova, Vladimirov, , , , (1987). [The ceruloplasmin-transferrin antioxidant system during hyperbaric oxygenation in rats]. Biulleten’ eksperimental’noi biologii i meditsiny, 1987 Sep;104(9):281-3. https://www.ncbi.nlm.nih.gov/pubmed/3663907