Sleep-related movement disorders (SRMD) have been shown to increase the risk of cardiovascular diseases. However, the relationship between SRMD and stroke remains unclear. To explore the relationship between SRMD and stroke in the general population. Two cohorts of patients with SRMD and without SRMD were followed up for the occurrence of hemorrhagic and ischemic stroke. The study cohort enrolled 604 patients who were initially diagnosed as SRMD between 2000 and 2005. 2,416 age- and sex-matched patients without prior stroke were selected as the comparison cohort. A Cox-proportional hazard regression analysis was performed for multivariate adjustment.

Chou, Yin, Chen, Lin, Sung, Chung, Chien, Tsai, (2017). The potential impact of sleep-related movement disorders on stroke risk: a population-based longitudinal study. QJM : monthly journal of the Association of Physicians, 2017 Oct;110(10):649-655. https://www.ncbi.nlm.nih.gov/pubmed/28482057