The effectiveness of hyperbaric and anoxic radiation therapy has been analysed in relaton to local control of malignant disease. Pilot schemes have led to the adoption of two basic treatment regimes which have similar morbidity to conventional regimens, but within their limitations are shown here to greatly increase the response rate of the malignancies treated. The limitations of each method are established. It is the lack of appreciation of limitations which have prejudiced much opinion against such methods; this article attempts to put their true place in perspective.

Holt, , , , , , , , (1975). The principles of hyperbaric and anoxic radiotherapy. The British journal of radiology, 1975 Oct;48(574):819-26. https://www.ncbi.nlm.nih.gov/pubmed/811296