This study reports on the case of an elderly patient, with diabetes, and a bullous wound on the left big toe that led to an amputation of the first and second left toes. The amputation was because of deep injury as it was not able to heal with a conventional treatment. After completing the normal treatment and the removal of a bacterial infection in the lesion, the patient underwent a treatment that was based on a hydrogel gel (0.9% saline solution) and hyperbaric oxygen therapy (HBOT). After 60 sessions of the therapy, almost complete closure of the wound was observed. There were no reports of discomfort or infection during the treatment. After seven months of treatment almost complete healing was observed with no infection. This treatment appears to be effective and should be recommended for the treatment of DFUs.

Aguiar, Amaral, Rodrigues, de Souza, , , , , (2017). A diabetic foot ulcer treated with hydrogel and hyperbaric oxygen therapy: a case study. Journal of wound care, 2017 Nov;26(11):692-695. https://www.ncbi.nlm.nih.gov/pubmed/29131751