The use of hyperbaric oxygen therapy for the treatment of conditions of local or focal hypoxia is not new. The author discusses the potential benefits of hyperbaric oxygen in the treatment of chronic wounds when used as a part of a multidisciplinary wound care program. Rationale and mechanism of action are discussed along with possible adverse effects. Costs of care and limb salvage rates are considered.

Cianci, , , , , , , , (1994). Adjunctive hyperbaric oxygen therapy in the treatment of the diabetic foot. Journal of the American Podiatric Medical Association, 1994 Sep;84(9):448-55. https://www.ncbi.nlm.nih.gov/pubmed/7965694