Hyperbaric Oxygen Therapy (HBOT) Research for Cancer.
Abstract: Radionecrosis of the larynx is a debilitating disease associated with pain, dysphagia, respiratory obstruction, and, in some cases, the need for laryngectomy. Persistent poor wound healing can lead to death. A series of eight patients with advanced (grades...
Abstract: Traumatic, clostridial myonecrosis is a rare and serious complication of wounds. Nontraumatic, metastatic, clostridial myonecrosis may be caused by carcinoma of the large intestine. Nontraumatic myonecrosis becomes evident with localized pain, generalized...
Abstract: Anemia may often become a problem in the treatment of the cancer patient. There are insufficient clinical data to assess the overall importance of anemia in radiotherapy, but there is clear evidence that uncorrected anemia is detrimental to local tumor...
Abstract: It is proposed that hyperbaric oxygen fails in the clinical situation due to a high proportion (greater than 33%) of hypoxic cells in human tumours. The means of overcoming this problem are reviewed. Additional to hyperbaric oxygenation, moderate hypothermia...
Abstract: Dong, , , , , , , , (1986). [Experimental study on the killing effect of hyperbaric oxygen combined with photodynamic therapy on transplanted tumors in mice]. Zhonghua yi xue za zhi, 1986 Nov;66(11):658-61. https://www.ncbi.nlm.nih.gov/pubmed/3102010
Abstract: Physicians are aware of the association between massively contaminated wounds and clostridial myonecrosis, or gas gangrene. A far less common but equally devastating presentation is that of nontraumatic or spontaneous gas gangrene. The most frequently...
Abstract: While previous studies with three human tumor xenografts suggest that contact-resistance plays a major role in the response of these tumors to radiation, it remains possible that partial hypoxia may provide an alternate explanation. The present study was...
Abstract: Sensitization of hypoxic cells in tumors, by increasing their oxygen supply, has been attempted for at least 30 years. Only the use of hyperbaric oxygen has been shown unequivocally as a beneficial adjunct to radiotherapy; and even then, the number of sites...
Abstract: 104 patients with head and neck cancer were entered into a prospective controlled trial of radiotherapy in hyperbaric oxygen (HBO). The trial compared 10 fractions of radiotherapy in HBO with 30 fractions of radiotherapy in air. Survival and local control...