Abstract: DNA damage induced by reactive oxygen species (ROS) seems to play an important role in the induction of mutations and cancer. We have recently shown that hyperbaric oxygen (HBO) treatment of volunteers (i.e., exposure to 100% oxygen at a pressure of 2.5 ATA)...
Cancer
Hyperbaric Oxygen Therapy (HBOT) Research for Cancer.
[New approaches in neurosurgery and hyperbaric medicine–the importance of preventive and industrial medicine].
Abstract: Neurosurgical patients have been mainly treated by surgical procedures over the past decades. In addition, hyperbaric oxygen (HBO) therapy in neurosurgery has been used in patients with ischemic cerebrovascular diseases, head trauma, spinal damage,...
Midazolam premedication reduces propofol requirements for sedation during regional anesthesia.
Abstract: Propofol is often used for sedation during spinal anesthesia. We investigated the effects of midazolam premedication on the propofol requirements and incidence of complications during sedation. In a prospective randomized, controlled, and single-blinded...
Osteoradionecrosis of the cervical vertebrae and occipital bone: a case report and brief review of the literature.
Abstract: Osteoradionecrosis (ORN) is a common complication of radiation therapy. We present the first case reported in the literature of ORN involving the first and second cervical vertebrae and occipital bone in a patient who was treated with surgery and radiation...
Radiation therapy with hyperbaric oxygen at 4 atmospheres pressure in the management of squamous cell carcinoma of the head and neck: results of a randomized clinical trial.
Abstract: The purpose of this study was to present the results of a randomized trial evaluating HBO-4 in combination with hypofractionated radiation therapy in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Between April 1974 and...
Incidence of complicated healing and osteoradionecrosis following tooth extraction in patients receiving radiotherapy for treatment of nasopharyngeal carcinoma.
Abstract: A group of 43 patients requiring tooth extraction after radiotherapy for nasopharyngeal carcinoma (NPC) was studied retrospectively to determine the incidence of post-extraction complications. It was found that because of the method used in the delivery of...
[Rehabilitation, using prosthetic implants, in patients with cancer of the oral cavity].
Abstract: The number of patients treated for neoplasms of the oral cavity (by surgery and/or radiotherapy) requiring prosthesis rehabilitation using osteointegrated implants is increasing greatly. The objective of this research is to examine the correlation between...
Life table analysis and clinical evaluation of oral implants supporting prostheses after resection of malignant tumors.
Abstract: Seventeen mostly elderly patients, 13 men and 4 women, were consecutively admitted for implant-prosthodontic treatment after they had undergone resection of malignant tumors in the oral cavity. A total of 53 dental implants (ITI-Straumann) was placed, 12 in...
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide.
Abstract: In animal models carbogen (normobaric 95% oxygen, 5% carbon dioxide) provides significant enhancement of local tumor control with fractionated radiotherapy. This approach to radiosensitization has been evaluated in the treatment of patients with bladder...
