by Extivita | Aug 30, 2020 | Depression
Abstract Objective: Rumination is a maladaptive emotional-regulation strategy that is strongly associated with depression. Impaired executive function can lead to difficulties in disengaging from rumination, thus exacerbating depression. In this study, we inspect an...
by Kristy Andrews | May 13, 2020 | Depression
Abstract Reactive oxygen species (ROS) have vital roles in cellular signaling and in defence against invasive microorganisms. Excessive ROS generation and exhaustion of antioxidative defences trigger proinflammatory signaling, damaging vital macromolecules and...
by Kristy Andrews | Mar 1, 2016 | Depression, Magnesium
Abstract Magnesium is one of the most important elements in the human body and is involved in a number of biochemical processes crucial for the proper functioning of the cardiovascular, alimentary, endocrine, and osteoarticular systems. It also plays a vital...
by Kristy Andrews | May 6, 2015 | Depression
Abstract Background: To compare alterations of mitochondria DNA (mtDNA) copy number, single nucleotide polymorphisms (SNPs), and oxidative damage of mtDNA in clinically stable patients with major depressive disorder (MDD). Methods: Patients met DSM-IV diagnostic...
by Kristy Andrews | Mar 7, 2015 | Depression
Abstract Importance: The neuroinflammatory hypothesis of major depressive disorder is supported by several main findings. First, in humans and animals, activation of the immune system causes sickness behaviors that present during a major depressive episode (MDE), such...
by Kristy Andrews | Feb 6, 2015 | Depression
Abstract Background: Depressive disorder (DD), including recurrent DD (rDD), is a severe psychological disease, which affects a large percentage of the world population. Although pathogenesis of the disease is not known, a growing body of evidence shows that...
