Surgical excision and lay-open is a well-known technique for the treatment of sacrococcygeal pilonidal disease, which impairs a patient’s quality of life considerably since wound healing takes a substantial amount of time. It is known that with this method total healing period is longer, but recurrence rate of the disease is lower. The beneficial effects of hyperbaric oxygen (HBO₂) therapy on wound healing have been well established since it was first put into in clinical use. The purpose of this prospective randomized clinical trial was to investigate the effects of HBO₂ therapy on wound healing in the patients who had sacrococcygeal pilonidal disease and surgical treatment. Total epithelialization times of 12 patients (Group 1) who received surgical intervention were compared with those of 10 patients who had surgical intervention and HBO₂ therapy (Group 2). In both groups excised tissue volume, excised skin area, body mass index, blood hemoglobin, albumin levels, ages and duration of the complaints were recorded and there was no statistically significant difference in these parameters except albumin levels when compared. The complete epithelialization time was significantly shorter in Group 2 (50 ± 11 vs. 83 ± 18, p⟨0.001). We conclude that HBO₂ had beneficial effects on wound healing, in the patients who had sacrococcygeal pilonidal disease and were treated with surgical excision applying lay-open technique.

Ersoz, Arikan, Sari, Korpinar, Ozcan, Poyraz, Purisa, Toklu, (). Effect of hyperbaric oxygen treatment on pilonidal disease surgery. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, ;43(7):821-825. https://www.ncbi.nlm.nih.gov/pubmed/28777519