Hyperbaric oxygen can be a useful adjuvant in the management of diabetic foot wounds when coordinated with medical-surgical management of the patient. Elevated tissue oxygen tensions improve leukocyte bacterial killing efficiency and enhance connective tissue regenerative systems for wound healing. An algorithm for the management of diabetic foot wounds is proposed in this article.

Brakora, Sheffield, , , , , , , (1995). Hyperbaric oxygen therapy for diabetic wounds. Clinics in podiatric medicine and surgery, 1995 Jan;12(1):105-17. https://www.ncbi.nlm.nih.gov/pubmed/7720026