Follow-up data at five years are reported for 24 patients with squamous cell carcinoma of the head and neck, included in a randomised prospective MRC study of radiotherapy in hyperbaric oxygen (10 fractions) or air (15 or 20 fractions). Although few, the data show a significant gain in local control (P less than 0.001) and survival (P less than 0.05) with the use of hyperbaric oxygen but no increased tissue reactions or morbidity.
Berry, Dixon, Ward, , , , , , (1979). The Leeds results for radiotherapy in HBO for carcinoma of the head and neck. Clinical radiology, 1979 Sep;30(5):591-2. https://www.ncbi.nlm.nih.gov/pubmed/466964