Sixty-nine patients with radiation necrosis were received by the authors from January 1, 1969 through August 1, 1975. The patients were categorized according to site of injury. Full treatment protocol is discussed including local wound care, antibiotic coverage, surgical procedures, and the administration of hyperbaric oxygen. Results indicate that the combination of hyperbaric oxygen, properly timed surgery, and antibiotic therapy has resulted in improvement in all cases of radiation necrosis and full healing in most.
Hart, Mainous, , , , , , , (1976). The treatment of radiation necrosis with hyperbaric oxygen (OHP). Cancer, 1976 Jun;37(6):2580-5. https://www.ncbi.nlm.nih.gov/pubmed/949677