Optic neuropathy resulting in permanent visual loss is an infrequent delayed complication of radiation therapy. Hyperbaric oxygen therapy (HBO) has been used to treat such a complication, but its efficacy is controversial. We report a patient who presented with radiation-induced optic neuropathy 17 months after irradiation for a left maxillary antrum melanoma. HBO fully reversed visual loss in the more recently involved eye, and slightly improved vision in the earlier affected eye.

Borruat, Schatz, Glaser, Feun, Matos, , , , (1993). Visual recovery from radiation-induced optic neuropathy. The role of hyperbaric oxygen therapy. Journal of clinical neuro-ophthalmology, 1993 Jun;13(2):98-101. https://www.ncbi.nlm.nih.gov/pubmed/8340486