Diagnosis Rheumatoid arthritis can be difficult to diagnose in its early stages because the early signs and symptoms mimic those of many other diseases. There is no one blood test or physical finding to confirm the diagnosis. During the physical exam, your doctor will...
Rheumatoid Arthritis
Hyperbaric Oxygen Therapy (HBOT) Research for Rheumatoid Arthritis
Diseases and Conditions Rheumatoid Arthritis
Fast Facts Rheumatoid arthritis (RA) is the most common type of autoimmune arthritis. It is caused when the immune system (the bodyâs defense system) is not working properly. RA causes pain and swelling in the wrist and small joints of the hand and...
Disease Modifying Anti-Rheumatic Drugs (DMARD)
Excerpt Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the...
Mechanisms for Joint Pain in Rheumatoid Arthritis (RA): from Cytokines to Central Sensitization
Abstract Purpose of review:Â Pain in rheumatoid arthritis (RA) may be due to different etiologies, ranging from peripheral inflammation to dysregulation of central nervous system (CNS) processing. This review evaluates relevant literature published on RA...
Hyperbaric Oxygen Alleviates the Inflammatory Response Induced by LPS Through Inhibition of NF-κB/MAPKs-CCL2/CXCL1 Signaling Pathway in Cultured Astrocytes.
Abstract: The purpose of this study was to investigate the inhibition neuroinflammation mechanisms of hyperbaric oxygen therapy (HBOT). Primary astrocytes were incubated with lipopolysaccharide (LPS) after which they underwent HBOT and separate administration of...
Effect of hyperbaric oxygen therapy on HMGB1/NF-κB expression and prognosis of acute spinal cord injury: A randomized clinical trial.
Although there are reports of the beneficial effects of hyperbaric oxygen (HBO) therapy in experimental settings, there are few clinical trials of HBO therapy for acute spinal cord injury (SCI). We investigated the effect of HBO in acute SCI by measuring plasma high mobility group box 1 (HMGB1) and nuclear factor kappa-B (NF-κB) levels, and by monitoring changes in electromyogram F-persistence (the percentage of discernible F-waves) and F-chronodispersion (the difference between minimal and maximal latency).
Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa
Abstract Because of the compartmentalization of disciplines that shaped the academic landscape of biology and biomedical sciences in the past, physiological systems have long been studied in isolation from each other. This has particularly been the case for the immune...
Attenuation of collagen-induced arthritis by hyperbaric oxygen therapy through altering immune balance in favor of regulatory T cells.
Abstract: Hyperbaric oxygen (HBOâ) therapy is currently used for the treatment of chronic wounds, radiation-induced soft tissue necrosis, several oxygen-deficiency conditions and decompression sickness. In addition to the current indications, much...
Erratum regarding inaccurate authorship attributions noted.
Abstract: For the paper entitled Pain improvement in rheumatoid arthritis with hyperbaric oxygen: report of three cases,' which appeared in the July-August 2016 issue of UHM (43-4), author attributions read as: John B. Slade MD, Mary V. Potts RN, Alan M. Flower DO,...